Welcome to Center for Complex Neurology, EDS & POTS.

 About Us

We provide expert diagnosis and treatment of selected diseases, including ALS, CIDP, Ehlers-Danlos Syndrome, (EDS), GBS, Neuropathy, Myositis, Muscular Dystrophy, Chiari Malformation, Myasthenia Gravis, Long COVID, Post-vaccine, POTS & other dysautonomias. Dr. Saperstein has over 20 years of experience diagnosing, treating and researching these conditions.

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David Saperstein, MD


The Center for Complex Neurology utilizes Klara as a tool to communicate with our patients. You can schedule an appointment, obtain refills, send us documents, or chat live with a member of our staff – all without making a single phone call! Kiss phone-tag goodbye!
Get started by clicking on the ‘Message Us’ box to the right of your screen.

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Patients Reviews

“Dr S helped me turn my life around with diagnosis and treatment that other doctors either missed or, in the interests of “thinking horses, not zebras”, rejected out of hand.
I may or may not have ever found another doctor to help me... but Dr S was there for me and has helped me get my Ehlers-Danlos Syndrome symptoms under control and my life moving in a positive direction again.”

Jared Rypka-Hauer

“I have been one of Dr. Saperstein’s patients since 2015. He has always taken care of me and listened to me. He has treated me for POTS, EDS, MCAD, and more. Due to insurance changes at Phoenix Neurological Associates, I haven’t been able to see him for a long time. I’ve tried other neurologists and facilities...but no one compares to Dr. Saperstein. He will work with you and your other doctors. He goes above and beyond. I’m forever thankful for his help.”

Chelsea Williams

“Dr. Saperstein and his staff are all kind and compassionate. He has been my Neurologist for almost 9 years, and diagnosed me with a rare neuromuscular disease for which I had seen several other doctors, and they were unable to diagnose it. I would recommend him to anyone having the neurological issues he treats. I’m so grateful for his kindness, and his brilliance in his field.”

Nancy Hammer

“After suffering for 35 years I finally got a diagnosis from Dr. Saperstein today! It's life-changing for me! The doc and his staff are awesome and treated me with compassion and understanding. Thank you all so very much!”

Kassie Corso Benoit

“I am a physician in Arizona. I can say without reservation that Dr. Saperstein is the BEST neurologist in the state and likely the southwestern U.S. Dr. Saperstein is knowledgeable, kind, compassionate, professional, and dedicated. His staff is dedicated to helping Dr. Saperstein provide the highest level of care to all of his patients. His level of knowledge is well beyond the level of his peers and he is a throwback to an era when the doctor really "Cared" for their patients. I would recommend without hesitation that all patients in need of a neurologist seek out Dr. Saperstein as his diagnostic skills are unparalleled. I had seen a host of neurologists throughout the country and no one can compare to his combination of compassion, diagnostic instincts, and his commitment to his patients and his profession. I recommend Dr. Saperstein with the highest level of confidence of my family and my patients. Andrew Rabinowitz MD”

Andrew Rabinowitz, MD

“Dr. Saperstein (and staff) were professional, compassionate and knowledgeable. I traveled with my daughter from Las Vegas and it was very much worth the trip. After six years of being misdiagnosed and dismissed by other medical professionals we finally have an accurate diagnosis, a plan and hope. Dr. Saperstein listened to my daughter and did a thorough examination. We both left the office more optimistic than we have felt in years....thank you again”

Michele Bauman

“I took my daughter there a couple of weeks ago. After years of various doctors that didn't empathize or understand her EDS or POTS, it was refreshing to finally meet a doctor who understood what she was going through, didn't trivialize her symptoms or make her feel crazy. Everyone there was compassionate, took their time to listen, asked excellent questions, and were very knowledgeable about these disorders that seem to be mysterious to the rest of the doctor's we've had. I am so grateful to Dr. Saperstein and the center for Complex Neurology for giving us hope for the future.”

Luz Marizza Bailey

“There really isn't anyone or anything comparable to Dr.Saperstein. Whether i was seeing him for the first time at 15 years old to now he has always consistently made me feel safe and cared for. He doesn't give up. Every time I bring up a new symptom or want to change up my routine he's always a message away and typically calls me within the day about it. Following to his new clinic that specifically focuses on my community that share the same rare illnesses as me is a huge step into becoming more visible. He wants to help in any way he can but more importantly he cares about my well being way more than I ever could have expected and having him as the lead on my case has been a very productive move. He works and refers to other knowledgeable physicians and truly never ever gives up. I'm not the most ideal patient as I have a few reserves to testing but he is patient every step of the way. The rest of my medical team knows their place in my care because of how much they respect Dr Saperstein and how much he's done for me and others. If you have a chance, please go see Dr. Saperstein. He saved my life and gave me so much more than just a handful of meds and some dry humor, he gave me hope that one day I'll be able to live semi normally and faith that research is coming, and that there is a big and loud advocate that's ready to tackle dysautonomia and all the other bs that comes with it. That advocate is Saperstein and with the help of his dazzle of zebras I think it's safe to say, he's got this.”

Brooke B. - Paradise Valley Village, Phoenix, AZYelp Review