ABOUT US
About the Center for Complex Neurology, EDS & POTS
The Center of Complex Neurology, EDS & POTS, specializes in disorders of nerve, muscle, and the autonomic nervous system. They are one of the very few sites worldwide that provides comprehensive diagnosis and management of Ehlers-Danlos Syndrome (EDS), neuropathy, CIDP, GBS, myositis, muscular dystrophy, myasthenia gravis, ALS, postural orthostatic tachycardia syndrome (POTS), and other dysautonomias.
Meet Dr. David Saperstein

David Saperstein, MD, Director at the Center for Complex Neurology, EDS & POTS
Clinical Associate Professor of Neurology, University of Arizona College of Medicine, Phoenix, AZ
The Center for Complex Neurology, EDS & POTS specializes in disorders of nerve, muscle, autonomics, and Ehlers-Danlos Syndrome (EDS)
Dr. Saperstein has cared for over 2,500 patients with EDS, POTS and related conditions. This has allowed him and his team to attain key knowledge and skills necessary to diagnose and manage patients with these disorders. There can be many other conditions that complicate the clinical picture, to include mast cell activation syndrome (MCAS), craniocervical instability (CCI), spinal fluid leaks, migraines, small fiber neuropathy, autoimmune disorders, as well as inflammatory and infectious diseases. The Center for Complex Neurology, EDS & POTS has state-of-the-art tools for diagnosing and treating these.
Dr. Saperstein and his team believe it is important to listen to their patients and pride themselves on delivering empathetic and thorough care. In recognition of this, Dr. Saperstein was the 2021 recipient of the Community Choice Award for Healthcare Professionals from The Ehlers-Danlos Society and also awarded the 2024 Physician of the Year by Dysautonomia International. Being recognized this way was a huge honor and you will see the plaques displayed in the office upon your visit.
In addition to his experience with patients with EDS and related conditions, Dr. Saperstein has over 25 years of experience as a neurologist, giving him valuable insight into troubling and complex complications, such as Chiari malformation, craniocervical instability (CCI), spinal fluid leaks, migraines, cognitive disorders, and neuropathy.
He is a Clinical Associate Professor of Neurology at the University of Arizona College of Medicine in Phoenix. Drawing upon over two decades of experience in diagnosing and managing patients with complex nerve and muscle conditions such as CIDP (and other immune-mediated neuropathies), myasthenia gravis, and myositis, he is available to provide expert care for patients with these conditions as well.
Dr. Saperstein is currently undergoing treatment for cancer and doing very well. He continues to oversee all aspects of patient care, meet with his team daily, and see patients via telemedicine. Following his next treatment, he plans to re-evaluate his schedule and hopes to expand appointment availability soon.